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Catalog Number | orb1306932 |
---|---|
Category | Small Molecules |
Description | Zotepine |
CAS Number | 26615-21-4 |
Purity | 99.67% |
MW | 331.86 |
SMILES | O(CCN(C)C)C=1C=2C(SC=3C(C1)=CC=CC3)=CC=C(Cl)C2 |
Formula | C18H18ClNOS |
Biological Activity | Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second-generation antipsychotic with a primary use as a treatment for schizophrenia, although clinical trials have been conducted into its efficacy as an antimanic agent in patients with acute bipolar mania. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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