Zotarolimus

• Catalog Number: orb611657
• Category: Small Molecules
• Description: Zotarolimus (ABT-578, A 179578) is a semi-synthetic analogue of rapamycin, inhibits FKBP-12 binding with IC50 of 2.8 nM and shows less potent systemic immunosuppression than rapamycin.
• CAS Number: [221877-54-9]
• MW: 966.21
• SMILES: CO[C@@H]1C(C)=CC=CC=C[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(C)=C[C@@H](C)C(=O)C[C@@H]([C@@H](C[C@@H]2CC[C@H](N3C=NN=N3)[C@H](OC)C2)C)OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@@]2(O)[C@@H](CC[C@H](O2)C1)C |c:23,t:4,6,8,&1:2,10,13,17,20,25,30,31,33,36,42,50,60,62,65|
• Formula: C₅₂H₇₉N₅O₁₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.