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Catalog Number | orb1980262 |
---|---|
Category | Small Molecules |
Description | Zilovertamab vedotin |
Biological Activity | Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate consisting of the humanized monoclonal antibody zilovertamab linked to the anti-microtubule cytotoxin monomethyl auristatin E (MMAE). Upon binding to ROR1 on tumor cells, zilovertamab vedotin is rapidly internalized and directed to lysosomes where the conjugate undergoes cleavage, releasing MMAE. This process induces apoptosis in the targeted cells. Zilovertamab vedotin has potential applications in cancer research [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
MMAE |
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