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Catalog Number | orb1306414 |
---|---|
Category | Small Molecules |
Description | Zaprinast |
CAS Number | 37762-06-4 |
Purity | 99.73% |
MW | 271.27 |
SMILES | O(CCC)C1=C(C=CC=C1)C=2NC3=C(C(=O)N2)NN=N3 |
Formula | C13H13N5O2 |
Biological Activity | Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through anti-proliferative and pro-apoptotic effects. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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