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Z-VAD-FMK
Catalog Number: orb1147018
| Catalog Number | orb1147018 |
|---|---|
| Category | Proteins |
| Description | Pan-caspase inhibitor; Peptides. |
| CAS Number | 187389-52-2 |
| Benzyloxycarbonyl (Z) at N terminal, Fluoromethylketone (FMK) at C terminal. | |
| Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone | |
| Caspases | |
| Form/Appearance | White lyophilised solid |
| Purity | > 98% by TLC |
| MW | 467.49 Da |
| Formula | C22H30FN3O7 |
| Solubility (25°C) | Soluble to 10 mg/mL in DMSO |
| Protein Sequence | Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone |
| Storage | Store dry, dark and frozen |
| Alternative names | 187389-52-2PI250, Z-VAD-FMK, Z-Val-Ala-Asp(OMe)-FM Read more... |
| Background | Z-VAD-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable, irreversible pan-caspase inhibitor. Z-VAD-FMK inhibits caspase processing and apoptosis induction in tumour cells in vitro with an IC50 of 0.0015 - 5.8 mM). Z-VAD-FMK is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Z-VAD-FMK is active in vivo and can inhibit apoptosis in numerous settings. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Z-VAD-FMK [orb1300137]
99.79%
161401-82-7
453.46
C21H28FN3O7
1 mg, 5 mg, 10 mg, 25 mg, 100 mg, 50 mg, 200 mg, 1 ml x 10 mm (in DMSO)- Item 1 of 1
- Item 1 of 1
