(Z)-4EGI-1

• Catalog Number: orb1693165
• Category: Small Molecules
• Description: (Z)-4EGI-1
• CAS Number: 901787-88-0
• MW: 451.28
• SMILES: N(/N=C(/CC1=C(N(=O)=O)C=CC=C1)\C(O)=O)C2=NC(=CS2)C3=CC(Cl)=C(Cl)C=C3
• Formula: C₁₈H₁₂Cl₂N₄O₄S
• Biological Activity: (Z)-4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, (Z)-4EGI-1 possesses anticancer activity[1][2].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.