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Catalog Number | orb1298541 |
---|---|
Category | Small Molecules |
Description | YUM70 |
CAS Number | 423145-35-1 |
Purity | 98.01% |
MW | 398.84 |
SMILES | C(NC(CCC)=O)(C1=C(O)C2=C(C(Cl)=C1)C=CC=N2)C=3C=C4C(=CC3)OCO4 |
Formula | C21H19ClN2O4 |
Biological Activity | YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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