Y 39983HCl

• Catalog Number: orb1146580
• Category: Small Molecules
• Description: Y-39983, also known as Y-33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK. Y-39983 attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination. Y-39983 downregulates RhoA/Rho-associated kinase expression during its promotion of axonal regeneration. Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.
• CAS Number: [471843-75-1]
• MW: 316.7859
• SMILES: Cl[H].O=C(C1C([H])=C([H])C(=C([H])C=1[H])[C@@]([H])(C([H])([H])[H])N([H])[H])N([H])C1C([H])=C([H])N=C2C=1C([H])=C([H])N2[H]
• Formula: C₁₆H₁₇CLN₄O
• Hazard Information: Non-Toxic
• Note: For research use only
• Expiration Date: 12 months from date of receipt.