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XRD-0394

XRD-0394

Catalog Number: orb2565042

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Catalog Numberorb2565042
CategorySmall Molecules
DescriptionXRD-0394 is a highly effective and selective dual inhibitor of ATM and DNA-PKcs, exhibiting oral bioactivity. It notably increases tumor cell destruction both in vitro and in vivo when combined with therapeutic ionizing radiation. Furthermore, XRD-0394 enhances the efficacy of PARP and topoisomerase I inhibitors in vitro [1].
CAS Number2595308-10-2
Purity98.00%
MW527.61
SMILESO=C1C2(C=3C=4C(N=CC3N1C)=CC(F)=C(C4)C=5C=C(NS(C)(=O)=O)C(OCCNC(C)C)=NC5)CCC2
FormulaC26H30FN5O4S
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.