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XE 991 dihydrochloride
Catalog Number: orb1307601
| Catalog Number | orb1307601 |
|---|---|
| Category | Small Molecules |
| Description | XE 991 dihydrochloride |
| CAS Number | 122955-13-9 |
| Purity | 98.96% |
| MW | 449.37 |
| SMILES | Cl.Cl.O=C1c2ccccc2C(Cc2ccncc2)(Cc2ccncc2)c2ccccc12 |
| Formula | C26H22Cl2N2O |
| Biological Activity | XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively). |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
