XE 991 dihydrochloride

• Catalog Number: orb1307601
• Category: Small Molecules
• Description: XE 991 dihydrochloride
• CAS Number: 122955-13-9
• Purity: 98.96%
• MW: 449.37
• SMILES: Cl.Cl.O=C1c2ccccc2C(Cc2ccncc2)(Cc2ccncc2)c2ccccc12
• Formula: C₂₆H₂₂Cl₂N₂O
• Biological Activity: XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.