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WZ4002-hydroxy

WZ4002-hydroxy

Catalog Number: orb1985188

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Catalog Numberorb1985188
CategorySmall Molecules
DescriptionWZ4002-hydroxyl is a WZ4002 derivative or WZ4002 analogue in which methoxy is replaced by hydroxyl and can be detected in 50% of patients with clinical resistance to gefitinib or erlotinib. WZ4002 has a basic chemical skeleton (covalent pyrimidine) that differs from other EGFR inhibitors.
Purity98.00%
MW480.95
SMILESC=CC(NC1=CC=CC(OC2=NC(NC3=CC=C(C=C3O)N4CCN(CC4)C)=NC=C2Cl)=C1)=O
FormulaC24H25ClN6O3
Biological ActivityWZ4002-hydroxyl is a WZ4002 derivative or WZ4002 analogue in which methoxy is replaced by hydroxyl and can be detected in 50% of patients with clinical resistance to gefitinib or erlotinib. WZ4002 has a basic chemical skeleton (covalent pyrimidine) that differs from other EGFR inhibitors.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.