WYE-354

• Catalog Number: orb746354
• Category: Small Molecules
• Description: WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50?= 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2.1,2?It is a much weaker inhibitor of phosphatidylinositol 3-kinase α (IC50?= 1026 nM) and other kinases.3?WYE-354 i
• CAS Number: [1062169-56-5]
• MW: 495.5
• SMILES: COC(NC1=CC=C(C2N=C3N(C4CCN(C(OC)=O)CC4)N=CC3=C(N3CCOCC3)N=2)C=C1)=O
• Formula: C₂₄H₂₉N₇O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.