WP1066

• Catalog Number: orb1306297
• Category: Small Molecules
• Description: WP1066
• CAS Number: 857064-38-1
• Purity: 99.07%
• MW: 356.22
• SMILES: C(=C(/C(N[C@@H](C)C1=CC=CC=C1)=O)\C#N)\C=2N=C(Br)C=CC2
• Formula: C₁₇H₁₄BrN₃O
• Biological Activity: WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.