VUF11207 fumarate

SKU: orb1308944

Description

VUF11207 fumarate is a potent and selective CXCR7 agonist with a pKi of 8.1. This small molecule is a valuable research tool for investigating CXCR7's role in chemokine signaling, cancer biology, and inflammation in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1785665-61-3
• MW: 586.65
• Purity: 99.50%
• Formula: C₃₁H₃₉FN₂O₈
• SMILES: OC(=O)\C=C\C(O)=O.COc1cc(cc(OC)c1OC)C(=O)N(CCC1CCCN1C)C\C(C)=C\c1ccccc1F
• Target: Arrestin,CXCR
• Solubility: DMSO:247 mg/mL (421.03 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.52 mM)

Bioactivity

• Target IC50:
  CXCR7:8.1 (pki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CXCR7, CXC chemokine receptors, CXCR, bone resorption, LPS, inhibit, Inhibitor, osteoclast precursor cells, osteoclastogenesis, RANKL, TnF?α, VUF11207, VUF-11207, VUF11207 fumarate, VUF11207 Fumarate, VUF-11207 fumarate, VUF-11207 Fumarate, VUF 11207, VUF 11207 Fumarate

Compound Identifiers

PubChem CID

90488970