VU-29

• Catalog Number: orb1305613
• Category: Small Molecules
• Description: VU-29
• CAS Number: 890764-36-0
• Purity: 99.47%
• MW: 384.39
• SMILES: N(C(=O)C1=CC=C(N(=O)=O)C=C1)C=2N(N=C(C2)C3=CC=CC=C3)C4=CC=CC=C4
• Formula: C₂₂H₁₆N₄O₃
• Biological Activity: VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.