Voriconazole

• Catalog Number: orb134756
• Category: Small Molecules
• Description: Voriconazole is an ergosterol biosynthesis inhibitor, as well as systemic antifungal. This compound, like many antifungal agents, is an inhibitor of CYP2C9, an enzyme involved in the oxidative metabolism of many xenobiotics.
• CAS Number: [137234-62-9]
• MW: 349.31
• SMILES: FC1=CC=C([C@@]([C@H](C2=NC=NC=C2F)C)(O)CN3N=CN=C3)C(F)=C1
• Formula: C₁₆H₁₄F₃N₅O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

H Elsaman, E Golubtsov, S Brazil, N Ng, I Klugherz, R Martin, K Dichtl, C Müller, J Wagener Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus Nature Communications, (2024)

PubMed:

Chemical structure of voriconazole