Venetoclax N-oxide

• Catalog Number: orb1983276
• Category: Small Molecules
• Description: Venetoclax N-oxide is an impurity of Venetoclax, a highly potent, selective, and orally bioavailable inhibitor of Bcl-2, with a Ki value of less than 0.01 nM (ABT-199; GDC-0199) [1].
• CAS Number: 2469279-00-1
• Purity: 98.00%
• MW: 884.44
• SMILES: CC1(C)CCC(CN2(=O)CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1
• Formula: C₄₅H₅₀ClN₇O₈S
• Biological Activity: Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199), a highly potent, selective, and orally bioavailable inhibitor of Bcl-2, demonstrates a Ki value of less than 0.01 nM [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.