Vandetanib trifluoroacetate

• Catalog Number: orb1685864
• Category: Small Molecules
• Description: Vandetanib trifluoroacetate
• CAS Number: 338992-53-3
• Purity: 98%
• MW: 589.38
• SMILES: O=C(O)C(F)(F)F.FC1=CC(Br)=CC=C1NC=2N=CN=C3C=C(OCC4CCN(C)CC4)C(OC)=CC32
• Formula: C₂₄H₂₅BrF₄N₄O₄
• Biological Activity: Vandetanib trifluoroacetate (D6474 trifluoroacetate) is an orally active and potent VEGFR2/KDR tyrosine kinase inhibitor with an IC50 value of 40 nM. Vandetanib trifluoroacetate also showed inhibition of VEGFR3/FLT4 and EGFR/HER1, with IC50 values of 110 nM and 500 nM respectively.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.