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Catalog Number | orb1306129 |
---|---|
Category | Small Molecules |
Description | Vacuolin-1 |
CAS Number | 351986-85-1 |
Purity | 99.45% |
MW | 577.42 |
SMILES | Ic1cccc(\C=N\Nc2nc(nc(n2)N2CCOCC2)N(c2ccccc2)c2ccccc2)c1 |
Formula | C26H24IN7O |
Biological Activity | Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
351986-85-1 | |
577.4 | |
C26H24IN7O |