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Catalog Number | orb1306129 |
---|---|
Category | Small Molecules |
Description | Vacuolin-1 |
CAS Number | 351986-85-1 |
Purity | 99.45% |
MW | 577.42 |
SMILES | IC1=CC=CC(\C=N\NC2=NC(=NC(=N2)N2CCOCC2)N(C2=CC=CC=C2)C2=CC=CC=C2)=C1 |
Formula | C26H24IN7O |
Biological Activity | Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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