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Catalog Number | orb216846 |
---|---|
Category | Proteins |
Description | Urocortin Human peptide |
CAS Number | 176591-49-4 |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
MW | 4696.3 |
Formula | C204H337N63O64 |
Protein Sequence | H-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2 |
Source | Synthetic |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Note | For research use only |
Application notes | Using a genomic library, human urocortin (UCN) has been cloned and localized to human chromosome 2. Human and rat urocortin share 95% identity within the mature peptide region. Human urocortin binds with high affinity to CRF receptor types 1, 2α, and 2β, stimulates cAMP accumulation from cells transfected with these receptors and acts in vitro to release ACTH from dispersed rat anterior pituitary cells. |
Expiration Date | 12 months from date of receipt. |
Human | |
6.25 pg/mL-400 pg/mL | |
1.56 pg/mL |
Greater than 90% as determined by SDS-PAGE. | |
17.4 kDa | |
E.coli |