Urocortin, human

• Catalog Number: orb2655244
• Category: Small Molecules
• Description: Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively. Urocortin human can be used as a test compound for studying the impact of corticotropin-releasing factor (CRF) receptor agonist and antagonist on sleep-wake patterns in conscious rats by using radiotelemetry system.
• CAS Number: 176591-49-4
• Purity: > 98% (HPLC)
• MW: 4696.2
• Formula: C₂₀₄H₃₃₇N₆₃O₆₄
• Target: Ki: 0.4 nM (hCRF1, cell assay), 0.3 nM (rCRF2α, cell assay), and 0.5 nM (mCRF2β, cell assay)
• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Note: For research use only
• Expiration Date: 12 months from date of receipt.