UNC0646

• Catalog Number: orb1296112
• Category: Small Molecules
• Description: UNC0646
• CAS Number: 1320288-17-2
• Purity: 100%
• MW: 621.9
• SMILES: N(C=1C2=C(N=C(N1)N3CCN(C(C)C)CCC3)C=C(OCCCN4CCCCC4)C(OC)=C2)C5CCN(CC5)C6CCCCC6
• Formula: C₃₆H₅₉N₇O₂
• Biological Activity: UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.