UNC0646

• Catalog Number: orb1296112
• Category: Small Molecules
• Description: UNC0646
• CAS Number: 1320288-17-2
• Purity: 100%
• MW: 621.9
• SMILES: COc1cc2c(NC3CCN(CC3)C3CCCCC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C
• Formula: C₃₆H₅₉N₇O₂
• Biological Activity: UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.