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UBE2S Protein, Human, Recombinant (GST)
Catalog Number: orb1961190
| Catalog Number | orb1961190 |
|---|---|
| Category | Proteins |
| Description | Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. |
| Tag | N-GST |
| Purity | 98.00% |
| MW | 50 KDa (reducing condition) |
| UniProt ID | Q16763 |
| Protein Sequence | Met1-Leu222 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. |
| Expression Region | Met1-Leu222 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
Human UBE2S protein [orb392668]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μg
