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U0126

U0126

Catalog Number: orb1705125

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Catalog Numberorb1705125
CategorySmall Molecules
DescriptionU0126
CAS Number109511-58-2
Purity98%
MW380.49
SMILESN#CC(=C(SC=1C=CC=CC1N)N)C(C#N)=C(SC=2C=CC=CC2N)N
FormulaC18H16N6S2
Biological ActivityU0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively. U0126 inhibits autophagy and mitophagy.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • (2Z,3Z)-U0126 [orb1739654]

    0.98

    218601-62-8

    380.49

    C18H16N6S2

    25 mg, 100 mg, 50 mg
  • U0126 [orb546009]

    > 98%

    109511-58-2

    380.49

    C18H16N6S2

    25 mg, 5 mg
  • U0126 [orb2666746]

    99% by HPLC

    109511-58-2

    380.49 Da

    C18H16N6S2

    5 mg
  • U0126-EtOH [orb1300964]

    98.65%

    1173097-76-1

    426.6

    C20H22N6OS2

    100 mg, 25 mg, 5 mg, 10 mg, 50 mg, 1 ml x 10 mm (in DMSO)
  • U0126-EtOH [orb1102148]

    > 98%

    [1173097-76-1]

    426.6

    C20H22N6OS2

    20 mg