TX1-85-1

• Catalog Number: orb1307642
• Category: Small Molecules
• Description: TX1-85-1
• CAS Number: 1603845-32-4
• Purity: 98.12%
• MW: 580.68
• SMILES: CC(=O)N1CCN(CC1)C1CCC(CC1)n1nc(-c2ccc(Oc3ccccc3)c(NC(=O)C=C)c2)c2c(N)ncnc12
• Formula: C₃₂H₃₆N₈O₃
• Biological Activity: TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.