Tuvusertib

• Catalog Number: orb1710368
• Category: Small Molecules
• Description: ATR inhibitor 1
• CAS Number: 1613200-51-3
• Purity: 98%
• MW: 370.32
• SMILES: C(NC=1C(=C(F)C=NC1)C2=CN=CN2C)(=O)C3=C4N(N=C3N)C=C(F)C=N4
• Formula: C₁₆H₁₂F₂N₈O
• Biological Activity: Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.