TTC-352

• Catalog Number: orb1739081
• Category: Small Molecules
• Description: TTC-352
• CAS Number: 1607819-68-0
• Purity: 0.98
• MW: 352.38
• SMILES: O(C1=C(C=2C(S1)=CC(O)=CC2)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4
• Formula: C₂₀H₁₃FO₃S
• Biological Activity: TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.