You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1739081 |
---|---|
Category | Small Molecules |
Description | TTC-352 |
CAS Number | 1607819-68-0 |
Purity | 0.98 |
MW | 352.38 |
SMILES | O(C1=C(C=2C(S1)=CC(O)=CC2)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4 |
Formula | C20H13FO3S |
Biological Activity | TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Filter by Rating