TRP1 / Tyrosinase-Related Protein-1 Antibody

• Catalog Number: orb606789
• Category: Antibodies
• Description: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
• Species/Host: Rabbit
• Clonality: Recombinant
• Clone Number: TYRP1/1564R
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Rabbit IgG, kappa
• Immunogen: Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Purity: Protein A affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This recombinant TYRP1 antibody is available for research use only.
• UniProt ID: P17643
• Storage: Store the recombinant TYRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.

IHC testing of FFPE human melanoma with recombinant TYRP1 antibody, HRP secondary and AEC chromogen. HIER: steam sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min.

SDS-PAGE analysis of purified, BSA-free recombinant TYRP1 antibody (clone TYRP1/1564R) as confirmation of integrity and purity.