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Catalog Number | orb1686055 |
---|---|
Category | Small Molecules |
Description | Trimetrexate glucuronate |
CAS Number | 82952-64-5 |
Purity | 98% |
MW | 563.564 |
SMILES | O[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O.COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC |
Formula | C25H33N5O10 |
Biological Activity | Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist that inhibits dihydrofolate reductase, which in turn blocks the synthesis of purine nucleotides and thymidylic acid, affecting DNA and RNA synthesis and exhibiting potential anti-tumour effects. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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