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Catalog Number | orb1307653 |
---|---|
Category | Small Molecules |
Description | Trabectedin |
CAS Number | 114899-77-3 |
Purity | 98% |
MW | 761.84 |
SMILES | [H][C@@]12[C@@H]3SC[C@]4(NCCc5cc(O)c(OC)cc45)C(=O)OC[C@H](N1[C@@H](O)[C@@H]1Cc4cc(C)c(OC)c(O)c4[C@H]2N1C)c1c2OCOc2c(C)c(OC(C)=O)c31 |
Formula | C39H43N3O11S |
Biological Activity | Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0.1 nM, 1.5 nM and 3.7 nM, respectively. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |