TpN15,17,47 (GST Tag) Protein

• Catalog Number: orb1921744
• Category: Proteins
• Description: Treponema pallidum, a spirochete of the family Spirochaetaceae, is the etiologic agent of venereal syphilis. Treponema pallidum has outer and cytoplasmic membranes, a thin peptidoglycan layer, and periplasmic flagella (also called endoflagella) which lie in the periplasmic space. Treponema pallidum Nichols (TpN) refers to a prefix of a nomenclature for the identification of Treponema pallidum polypepitides. TpN 15, a membrane-associated 15-kDa lipoprotein with signal peptide, induces antibody response during infection. TpN17 is a major membrane-associated 17-kDa lipoprotein with signal sequence. TpN 47, a major membrane-associated 47-kDa lipoprotein with carboxypeptidase properties, activates endothelial cells and has high immunogenicity. Reportedly, specific antibodies against the three Tp antigens have been continuously detectable in patients throughout the course of TP infection, which are considered to be the most promising for clinical appilication.
• Tested applications: CLIA, IA, LF
• Form/Appearance: Purified,Liquid
• Purity: > 90% pure (SDS-PAGE).
• MW: 35.83 kDa
• Source: E. coli
• Storage: For long term storage, the product should be stored at -20°C or lower.
• Note: For research use only
• Application notes: Recommended Applications: LFIA, CLIA, MIA. Test Methods: Self-produced antigen test; Test 10 Positive Reference Materials; Test Sample Extraction Solution, Test 10 normal Nasal Swab Samples
• Sample Types: Test sample type: Serum / Plasma / Whole Blood. Test sample source: Human
• Expiration Date: 6 months from date of receipt.