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Catalog Number | orb573277 |
---|---|
Category | Small Molecules |
Description | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM. |
CAS Number | [1558021-37-6] |
MW | 431.8264241 |
SMILES | ClC1=CC=C(OC2C=CC(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)=CN=2)C=C1 |
Formula | C20H18ClN3O6 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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