TP0427736 HCl

• Catalog Number: orb573383
• Category: Small Molecules
• Description: TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with a
• CAS Number: [864374-00-5]
• MW: 334.85
• SMILES: CC1=CSC(C2N=CNC=2C2=CC=C3N=CSC3=C2)=N1
• Formula: C₁₄H₁₁ClN₄S₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.