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Catalog Number | orb1089520 |
---|---|
Category | Small Molecules |
Description | Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib can be used for the research of multiple sclerosis (MS). |
CAS Number | [1971920-73-6] |
MW | 455.51 |
SMILES | O=C(N1[C@H]2CN(C(C=C)=O)CCC2)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C1C=CN=C5N |
Formula | C26H25N5O3 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1971920-73-6 |
99.20% | |
1971920-73-6 | |
455.51 | |
C26H25N5O3 |
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