Tivozanib(AV-951)

• Catalog Number: orb154729
• Category: Small Molecules
• Description: Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R.
• CAS Number: [475108-18-0]
• MW: 454.8631
• SMILES: ClC1C([H])=C(C([H])=C([H])C=1N([H])C(N([H])C1C([H])=C(C([H])([H])[H])ON=1)=O)OC1C([H])=C([H])N=C2C([H])=C(C(=C([H])C2=1)OC([H])([H])[H])OC([H])([H])[H]
• Formula: C₂₂H₁₉CLN₄O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Tivozanib(AV-951)