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Catalog Number | orb154729 |
---|---|
Category | Small Molecules |
Description | Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R. |
CAS Number | [475108-18-0] |
MW | 454.86306 |
SMILES | O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4 |
Formula | C22H19ClN4O5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of Tivozanib(AV-951)
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