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Catalog Number | orb2653192 |
---|---|
Category | Small Molecules |
Description | Tivozanib hydrochloride hydrate is a potent and selective and orally active VEGFR tyrosine kinase inhibitor with IC50of 0.21, 0.16, 0.24 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively. Tivozanib hydrochloride hydrate inhibits angiogenesis and vascular permeability in tumor tissues and shows antitumor activity. Tivozanib hydrochloride hydrate has the potential for the research of metastatic renal cell carcinoma (RCC) . |
CAS Number | [682745-41-1] |
MW | 509.339283466339 |
SMILES | ClC1C=C(C=CC=1NC(NC1C=C(C)ON=1)=O)OC1C=CN=C2C=C(C(=CC2=1)OC)OC.Cl.O |
Formula | C22H22CL2N4O6 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98% | |
682745-41-1 | |
509.34 | |
C22H22Cl2N4O6 |