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Catalog Number | orb1302863 |
---|---|
Category | Small Molecules |
Description | Tirapazamine |
CAS Number | 27314-97-2 |
Purity | 99.05% |
MW | 178.15 |
SMILES | O=N=1C2=C(N(=O)=NC1N)C=CC=C2 |
Formula | C7H6N4O2 |
Biological Activity | Tirapazamine (Win59075) is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents like cisplatin. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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