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Catalog Number | orb1706533 |
---|---|
Category | Small Molecules |
Description | Timapiprant sodium |
CAS Number | 950688-14-9 |
Purity | 98% |
MW | 371.367 |
SMILES | [Na].Cc1c(Cc2ccc3ccccc3n2)c2cc(F)ccc2n1CC(O)=OjcExt:v:0:0 |
Formula | C21H17FN2NaO2 |
Biological Activity | Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), human native DP2 (Ki=4 nM). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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