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Tidutamab

Tidutamab

Catalog Number: orb1980464

DispatchUsually dispatched within 5-10 working days
$ 550.00
Catalog Numberorb1980464
CategoryAntibodies
DescriptionTidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
CAS Number2148354-90-7
Concentration5.1 mg/mL
Purity98.00%
ConjugationUnconjugated
TargetTidutamab
Biological ActivityTidutamab (XmAb-18087) is a bispecific antibody (bsAb) that is both humanized and optimized for affinity, targeting the SSTR2 and CD3 domains to bind to the somatostatin receptor 2 (SSTR2) and T cells, respectively. It features a full Fc domain to ensure an extended serum half-life. This compound engages in the targeted elimination of SSTR2-positive tumor cells via the mechanism of redirected T cell-mediated cytotoxicity (RTcC) [1].
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NoteFor research use only
Expiration Date12 months from date of receipt.