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Catalog Number | orb1980464 |
---|---|
Category | Antibodies |
Description | Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors. |
CAS Number | 2148354-90-7 |
Concentration | 5.1 mg/mL |
Purity | 98.00% |
Conjugation | Unconjugated |
Target | Tidutamab |
Biological Activity | Tidutamab (XmAb-18087) is a bispecific antibody (bsAb) that is both humanized and optimized for affinity, targeting the SSTR2 and CD3 domains to bind to the somatostatin receptor 2 (SSTR2) and T cells, respectively. It features a full Fc domain to ensure an extended serum half-life. This compound engages in the targeted elimination of SSTR2-positive tumor cells via the mechanism of redirected T cell-mediated cytotoxicity (RTcC) [1]. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA, FC | |
Human | |
Chimeric Humanized | |
Monoclonal | |
Unconjugated |
ELISA, FC | |
Human | |
Chimeric Humanized | |
Monoclonal | |
Unconjugated |
FC | |
Human | |
Chimeric Humanized | |
Monoclonal | |
Unconjugated |
Recombinant | |
Unconjugated |