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Catalog Number | orb1299945 |
---|---|
Category | Small Molecules |
Description | THZ2 |
CAS Number | 1604810-84-5 |
Purity | 98% |
MW | 566.05 |
SMILES | ClC=1C(C=2C=3C(NC2)=CC=CC3)=NC(NC4=CC(NC(=O)C5=CC(NC(/C=C/CN(C)C)=O)=CC=C5)=CC=C4)=NC1 |
Formula | C31H28ClN7O2 |
Biological Activity | THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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