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Catalog Number | orb1982622 |
---|---|
Category | Small Molecules |
Description | THR-β agonist 6 |
CAS Number | 2791290-58-7 |
MW | 457.27 |
Formula | C20H14Cl2N6O3 |
Biological Activity | THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remarkable liver-to-serum ratio of 93:1 in mouse models, underscoring its efficacy and potential for research in nonalcoholic steatohepatitis (NASH) [1]. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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