THR-β agonist 6

• Catalog Number: orb1982622
• Category: Small Molecules
• Description: THR-β agonist 6
• CAS Number: 2791290-58-7
• MW: 457.27
• Formula: C₂₀H₁₄Cl₂N₆O₃
• Biological Activity: THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remarkable liver-to-serum ratio of 93:1 in mouse models, underscoring its efficacy and potential for research in nonalcoholic steatohepatitis (NASH) [1].
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.