TH-287 hydrochloride

• Catalog Number: orb611851
• Category: Small Molecules
• Description: TH287 hydrochloride is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 hydrochloride is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 μM. TH287 hydrochloride could act as a chemotherapeutic agent for cancer research.
• CAS Number: [1638211-05-8]
• MW: 305.5908
• SMILES: ClC1C(=C([H])C([H])=C([H])C=1C1=C([H])C(=NC(N([H])[H])=N1)N([H])C([H])([H])[H])Cl.Cl[H]
• Formula: C₁₁H₁₁CL₃N₄
• Note: For research use only
• Expiration Date: 12 months from date of receipt.