TG101209

• Catalog Number: orb181163
• Category: Small Molecules
• Description: TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 activity with IC50 of 130 nM.
• CAS Number: [936091-14-4]
• MW: 509.67
• SMILES: C(S(NC(C)(C)C)(=O)=O)1=CC=CC(NC2C(C)=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=2)=C1
• Formula: C₂₆H₃₅N₇O₂S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.