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| Catalog Number | orb146201 |
|---|---|
| Category | Small Molecules |
| Description | Teriflunomide: Teriflunomide, aslo know as A77 1726 (trade name Aubagio, marketed by Sanofi) is the active metabolite of leflunomide. |
| CAS Number | [163451-81-8] |
| MW | 270.21 |
| SMILES | C(NC1=CC=C(C(F)(F)F)C=C1)(=O)/C(/C#N)=C(\O)/C |
| Formula | C12H9F3N2O2 |
| Hazard Information | Non-Toxic |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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Groh, Janos et al. Immune modulation attenuates infantile neuronal ceroid lipofuscinosis in mice before and after disease onset Brain Commun, 3, (2021)
Applications
In vivo
Reactivity
Mouse
Hörner, Michaela et al. CNS-associated T-lymphocytes in a mouse model of Hereditary Spastic Paraplegia type 11 (SPG11) are therapeutic targets for established immunomodulators Exp Neurol, 355, 114119 (2022)
Applications
In vivo
Reactivity
Mouse
Groh, Janos et al. Fingolimod and Teriflunomide Attenuate Neurodegeneration in Mouse Models of Neuronal Ceroid Lipofuscinosis Mol Ther, 25, 1889-1899 (2017)
Applications
In vivo
Reactivity
Mouse
Chemical structure of Teriflunomide(A-771726).
