Tepoditamab

• Catalog Number: orb1980564
• Category: Antibodies
• Description: Tepoditamab (MCLA-117) is a bispecific monoclonal antibody targeting CLEC12A on myeloid cells and CD3 on cytotoxic T cells. As a myeloid differentiation antigen, CLEC12A allows the compound to eliminate AML leukemia progenitor and stem cells through T cell-mediated proliferative lysis, making it valuable in acute myeloid leukemia (AML) research [1].
• Clonality: Monoclonal
• CAS Number: 2044679-53-8
• Purity: 98.00%
• Conjugation: Unconjugated
• Target: Tepoditamab
• Biological Activity: Tepoditamab (MCLA-117) is a bispecific monoclonal antibody designed to target CLEC12A on myeloid cells and CD3 on cytotoxic T cells. CLEC12A serves as a myeloid differentiation antigen. The compound effectively eliminates AML leukemia progenitor and stem cells by inducing T cell-mediated proliferative lysis, making it a valuable asset in acute myeloid leukemia (AML) research [1].
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.