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Tebanicline tosylate

Tebanicline tosylate

Catalog Number: orb1693298

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Catalog Numberorb1693298
CategorySmall Molecules
DescriptionTebanicline tosylate
CAS Number198283-74-8
Purity98%
MW370.85
SMILESS(=O)(=O)(O)C1=CC=C(C)C=C1.O(C[C@H]1CCN1)C=2C=CC(Cl)=NC2
FormulaC16H19ClN2O4S
Biological ActivityTebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.