TCPOBOP

• Catalog Number: orb746314
• Category: Small Molecules
• Description: TCPOBOP is an agonist of the constitutive androstane receptor (CAR) (EC50 = 20 nM). TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents. TCPOBOP has been used for enhancing Mcl-1-Italics promoter functions in mouse hepatoma cells. TCPOBOP has also been used to study constitutive androstane receptor(CAR)-induced gene expression in mouse hepatocytes.
• CAS Number: [76150-91-9]
• MW: 402.052
• SMILES: ClC1=CN=C(OC2=CC=C(OC3=NC=C(Cl)C=C3Cl)C=C2)C(Cl)=C1
• Formula: C₁₆H₈Cl₄N₂O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.