TC-2153 HCl

• Catalog Number: orb1738662
• Category: Small Molecules
• Description: TC-2153 HCl
• CAS Number: 1381769-23-8
• Purity: 0.98
• MW: 355.8692
• SMILES: Cl.FC(F)(F)C1=CC=2SSSSSC2C(N)=C1
• Formula: C₇H₅ClF₃NS₅
• Biological Activity: TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.