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Catalog Number | orb1307447 |
---|---|
Category | Small Molecules |
Description | Tazemetostat |
CAS Number | 1403254-99-8 |
Purity | 99.72% |
MW | 572.74 |
SMILES | N(CC)(C1=C(C)C(C(NCC2=C(C)C=C(C)NC2=O)=O)=CC(=C1)C3=CC=C(CN4CCOCC4)C=C3)C5CCOCC5 |
Formula | C34H44N4O4 |
Biological Activity | Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epithelioid sarcoma/follicular lymphoma. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1467052-75-0 |
2750350-39-9 | |
605.72 | |
C34H43N3O7 |
1403255-00-4 | |
682.12 | |
C34H47Cl3N4O4 |
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