Tazemetostat hydrobromide

• Catalog Number: orb1307697
• Category: Small Molecules
• Description: Tazemetostat hydrobromide
• CAS Number: 1467052-75-0
• Purity: 99.03%
• MW: 653.65
• SMILES: O=C(C1=CC(C2=CC=C(CN3CCOCC3)C=C2)=CC(N(CC)C4CCOCC4)=C1C)NCC5=C(C)C=C(C)NC5=O.[H]Br
• Formula: C₃₄H₄₅BrN₄O₄
• Biological Activity: Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 nM). Tazemetostat hydrobromide also inhibits EZH1 (IC50: 392 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.